LncRNAs as new biomarkers to differentiate triple negative breast cancer from non-triple negative breast cancer
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چکیده
منابع مشابه
LncRNAs as new biomarkers to differentiate triple negative breast cancer from non-triple negative breast cancer
Triple negative breast cancer (TNBC) is an aggressive type of breast cancer with high heterogeneity. To date, there is no efficient therapy for TNBC patients and the prognosis is poor. It is urgent to find new biomarkers for the diagnosis of TNBC or efficient therapy targets. As an area of focus in the post-genome period, long non-coding RNAs (lncRNAs) have been found to play critical roles in ...
متن کاملClinicopathological Features of Non-metastatic Triple Negative Breast Cancer
Background: Triple negative breast cancer (TNBC) is reported to be associated with a high risk of recurrence, poor overall survival (OS), and disease-free survival (DFS) rates. This study evaluated the clincopathological features and survival of non-metastatic TNBC women in the capital of Iran compared with other areas of the world. Methods: In a retrospective study, 119 women with TNBC based ...
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Background: Previous data have shown the tumorigenicity roles of HDAC8 in breast cancer. More recently, the oncogenic effects of this molecule have been revealed in TNBC. The present study aimed to determine the diagnostic value of HDAC8 for the differentiation of TNBC from nTNBC tumors. Methods: A total of 50 cancerous and normal adjacent tumor specimens were obtained, and the clinical and pat...
متن کاملTriple-Negative Breast Cancer
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متن کاملTriple-Negative Breast Cancer
From the Program in Cancer Genetics, the Research Institute of the McGill University Health Centre, and the Lady Davis Institute of the Jewish General Hospital (W.D.F.); McGill University, Montreal; and the Breast Unit, Royal Marsden Hospital and Institute of Cancer Research (I.E.S.), and the Breakthrough Breast Cancer Research Centre, Institute of Cancer Research (J.S.R.-F.) — both in London. ...
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ژورنال
عنوان ژورنال: Oncotarget
سال: 2016
ISSN: 1949-2553
DOI: 10.18632/oncotarget.7509